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Frequently Asked Questions about Prostate Artery Embolization (PAE)

What is Prostate Artery Embolization (PAE)?

Prostate Artery Embolization (PAE) is a minimally invasive, image-guided procedure used to treat urinary symptoms caused by an enlarged prostate, also known as Benign Prostatic Hyperplasia (BPH). It works by reducing blood flow to the prostate, allowing the gland to gradually shrink and relieve pressure on the urethra.

PAE is performed to reduce symptoms associated with an enlarged prostate, such as frequent urination, difficulty starting urination, a weak urine stream, urinary urgency, incomplete bladder emptying, and urinary retention.

PAE may be considered for people with BPH whose symptoms have not improved sufficiently with medications, those who want to avoid or delay traditional prostate surgery, or patients whose medical conditions may increase the risks associated with surgery. Suitability is determined by a healthcare provider after an evaluation.

PAE may help improve several urinary symptoms associated with BPH, including:

  • Frequent or nighttime urination
  • Urinary urgency
  • Difficulty starting urination
  • Weak urine flow
  • Incomplete bladder emptying
  • Urinary retention

During PAE, a doctor guides a small catheter into the arteries supplying the prostate using real-time X-ray imaging. Tiny embolic particles are then delivered into these arteries to reduce blood flow to the prostate. Over time, the prostate gradually shrinks, which can relieve pressure on the urethra and improve urinary symptoms.

PAE is minimally invasive and does not require an incision into the prostate. A small catheter is inserted through an artery, usually through the wrist or groin, and guided to the prostate arteries.

The procedure typically takes about 1 to 3 hours. The exact duration depends on the anatomy of the prostate arteries and the complexity of the procedure.

Yes. Patients generally remain awake during the procedure. Local anesthesia is used at the catheter insertion site, and mild sedation may be provided to help you relax.

Most patients experience minimal discomfort. You may feel some pressure or mild discomfort at the catheter insertion site. A temporary warm sensation may occur when contrast dye is injected.

PAE is typically performed in a hospital or outpatient interventional radiology center.

Preparation may include a review of your medical history and medications, physical examination, prostate evaluation, blood and urine tests, and imaging such as ultrasound, MRI, or CT angiography. Your doctor may also recommend temporarily adjusting certain medications.

After local anesthesia is administered, a small catheter is inserted into an artery in the wrist or groin. Using real-time X-ray guidance, the catheter is directed to the arteries supplying the prostate. Contrast dye helps identify the prostate arteries, and tiny embolic particles are delivered to reduce blood flow. Both sides of the prostate are typically treated during the same procedure.

You will usually be monitored in a recovery area for several hours. Some patients experience temporary pelvic discomfort, urinary frequency, or burning during urination. Many patients can return home the same day or after a short observation period.

Recovery is generally short. Many patients can resume normal activities within a few days, depending on their individual recovery and their doctor’s instructions.

Improvement is usually gradual rather than immediate. Many patients begin noticing changes within several weeks, with continued improvement over the following months as the prostate gradually shrinks.

Potential benefits of PAE include improved urinary symptoms and urine flow, reduced urinary frequency and urgency, less nighttime urination, preservation of the prostate gland, a short recovery period, and avoidance of an incision into the prostate.

Yes. PAE does not remove the prostate. Instead, it reduces blood flow to the gland, allowing it to gradually shrink while preserving the prostate’s normal anatomy.

PAE can be an alternative treatment for some patients with BPH. It may be considered by people who want to avoid or delay prostate surgery or who may have medical conditions that increase surgical risk. Your doctor can determine whether PAE is appropriate for you.

Although PAE is generally considered safe, potential risks include bruising or bleeding at the catheter insertion site, temporary pelvic discomfort, increased urinary frequency or urgency, burning during urination, urinary tract infection, temporary blood in the urine, semen, or stool, allergic reactions to contrast dye, blood vessel injury, temporary urinary retention, and the possible need for additional treatment.

Serious complications are uncommon when PAE is performed by experienced specialists. However, every medical procedure has potential risks, and your doctor will discuss the risks and benefits based on your individual health.

Yes. Successful PAE can improve urine flow by reducing the size of the prostate and relieving pressure on the urethra.

PAE may reduce nighttime urination, also known as nocturia, as urinary symptoms associated with an enlarged prostate improve.

PAE may improve bladder emptying by reducing the obstruction caused by an enlarged prostate. The degree of improvement varies from person to person.

Yes. Follow-up appointments are generally scheduled to monitor your recovery, urinary symptoms, and treatment progress. Your physician will provide individualized follow-up instructions.

Although many patients experience improvement, symptoms may persist or additional treatment may sometimes be required. Your doctor can assess your symptoms and recommend the appropriate next steps.

The outcome varies between individuals. Successful treatment may lead to improved urine flow, reduced urinary frequency and urgency, better bladder emptying, fewer nighttime bathroom visits, and an improved quality of life.

Many patients are able to return home the same day after a period of observation. Some patients may require a longer observation period depending on their individual circumstances.

Many patients can resume normal activities within a few days. Your exact recovery time will depend on your condition and your physician’s recommendations.

No. PAE is not appropriate for every patient with BPH. A healthcare provider will evaluate your symptoms, prostate, medical history, medications, imaging results, and overall health before determining whether PAE is suitable.

If you have BPH symptoms that are affecting your daily life, discuss your treatment options with a qualified healthcare provider. They can evaluate your condition and explain whether PAE or another treatment approach may be appropriate.